Two Antibiotics Identified as gamma-Rubromycin and Crotonic Acid Produced by Streptomyces collinus NRC-11 Isolated from Egyptian Soils PDF

Keywords

antibiotics, Egypt, fermentation

Abstract

Streptomyces spp. NRC-11 was isolated from Egyptian soils. The organism was identified and shown to be identical to Streptomyces collinus. It produced two antibodies in the fermentation broth. The two antibodies were separated, purified and subjected to identification. The physico-chemical and biological properties of antibiotics are reported. Antibiotics A-1 and A-3 from filtrate and mycelium respectively, were identical to gamma- rubromycin; antibiotic A-2 was identified as crotonic acid.