Copper Complexes of Di-, Tri- and Tetra-Peptides Containing Tryptophan, Histidine and Arginine PDF

Keywords

histidine, tryptophan, arginine

Abstract

Fifty seven copper complexes of di-, and tri- and tetra-peptides containing tryptophan, histidine and arginine are studied spectrophotometrically. The lambda ,ax and color of the complex is dependent on the sequence of the amino acid in the dipeptide methyl esters of tryptophan and arginine; and independent on the sequence of dipeptides of histidine or in any of the tri- and tetra-peptides of histidine, arginine and tryptophan. The results achieved confirmed that the nitrogen atoms of the indole nucleus in tryptophan, imidazole ring in histidine and guanidino group in arginine do not participate in complex formation of all studied di-, tri- and tetra-peptides. However, the amide group and hydrazide group of dipeptide amide and dipeptide hydrazides participate in complex formation