Synthesis of Several New N-Substitutedmaleisoimides and Phthalisoimides Using Different Dehydrating Agents PDF

Keywords

Dehydrating agents, isoimides, structure determination

Abstract

Several new members of N- substitutedmaleisoimides and phthalisoimides are prepared. Four of these compounds are N- arylphthalisoimides, three are N- arylisomaleimides, and one is N-cycloprophylmaleisoimides. The yields of N(2- ethylphenyl) phthalisoimide and other isoimides were compared when the dehydration of the corresponding amic acids performed using trifluoroacetic anhydride (TFAA), ethyl chloroformate (ECF), and N, N-dicyclohexylcarbodiimide (DCC). Structure determination of the new compounds were based on IR, NMR and isomerization of the isoimides to the corresponding imides.