Isolation of Corynebacterium xerosis from Jordanian Soil and a Study on its Antimicrobial Activity against a Range of Bacteria and Fungi PDF

Keywords

Antifungal, Corynebacterium xerosis, Soil microorganisms, Antimicrobial, Substance, Resistant

Abstract

A bacterial strain which has been identified as Corynebacterium xerosis NB-2 was isolated from a soil sample from Jerash Private University, Jerash, Jordan. This isolate was found to produce an antimicrobial substance active only against filamentous fungi and yeasts (Aspergillus niger SQ 40, Fusarium oxysporum SQ 11, Verticillium dahliae SQ 42, Saccharomyces cerevisiae SQ 46 and Candida albicans SQ 47). However, all tested gram-positive bacteria and gram-negative bacteria (Bacillus megaterium SQ 5, Bacillus cereus SQ 6, Staphylococcus aureus SQ 9, Streptococcus pyogens SQ 10, Eschericshia coli SQ 22, Klepsiella spp SQ 33 and Pseudomonas mallei SQ 34) were found to be resistant. In batch culture, the isolate NB-2 produced the antimicrobial substance late in the growth phase and accumulated the main portion in their cells. The data presented in the present investigation exhibited a novel antimicrobial activity of Corynebacterium xerosis against filamentous fungi and yeasts which was not previously described.