Antimicrobial Substances Produced by Air Flora PDF

Keywords

Air flora, antibiotics, bacillus, cereus, circulans, megaterium

Abstract

Bacterial strains identified as Bacillus megaterium NB-3, Bacillus cereus NB-4, Bacillus cereus NB-5, Bacillus subtilis NB-6 and Bacillus circulans NB-7, were isolated from the air of Jerash Private University, Jerash, Jordan. They were found to produce several antimicrobial substances that exhibited potent antifungal activity against filamentous fungi and yeasts. Bacillus subtilis NB-6 showed activity against filamentous fungi, yeasts and gram-positive bacteria, while bacillus megaterium NB-3 exhibited a broad spectrum of activity against filamentous fungi, yeasts, gram-positive bacteria and gram-negative bacteria. In batch culture, the bacterial isolates produced the antibiotics late ub tge growth phase and accumulated a main portion in the culture fluids. The data presented in this study exhibit a novel source for the isolation of antimicrobial substances producing microorganisms in Jordan, which were not previously described. The isolation of these strains suggests their potential as a source od novel antibiotics.