Author(s): A.M. El-Gendy, M.El-Safty, A. Essawy and H.Y. Moustafa
Article publication date: 1988-12-01
Vol. 6 No. 3 (yearly), pp. 337-350.
161
Keywords
amines, benzoxazine, benzene, phosphorus
Abstract
The benzoxazine (I) reacted with primary amines and yielded the carbamoyl acetanilide derivatives (II a-c), and aniline in boiling benzene/ phosphorus oxychloride gave the quinazolinone (III). (I) reacted with secondary amines and gave the carbonyl acetanilide derivative (IV). Hydrazinolysis of (I) gave the quinazolinone (V a & b). Compound (V a) condensed with aromatic aldehydes and reacted with phosphorus pentasulphide to give (VI a-d) and (VII) respectively. The reaction of active methylene compounds with (I) gave (VIII) or (IX) respectively. Also (I) reacted with formamide to yield (X) and with sodium azide in boiling acetic acid to give (XI) and (XII) respectively.